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Heddle NM, Cook RJ, Webert KE, Sigouin C, Rebulla P, BEST Working Party.

Methodological Issues in the Use of Bleeding as an Outcome in Transfusion Medicine Studies.

Journal
Transfusion 2003;43:742-52.
Link
http://onlinelibrary.wiley.com/doi/10.1046/j.1537-2995.2003.00418.x/abstract