RADAR:foRmation of Anti D After RhIg

Despite the availability of RhIg prophylaxis, RhD alloimmunization still occurs. Literature on the etiologies of RhD
alloimmunization in the post-RhIg era is limited. Describing the suspected etiologies of RhD alloimmunization in a
large data set from multiple institutions could inform future strategies to reduce the rate of RhD alloimmunization.
In addition, the findings in this study may reveal the impact of healthcare disparities which limit access to essential
antenatal care, including RhIg. Understanding the etiologies of RhD alloimmunization in the post-RhIg era will lead
to improved strategies for prevention of HDFN.
In this multi-center retrospective descriptive study, data will be extracted from the laboratory information and
electronic medical record systems. New anti-D alloantibodies resulted by the blood bank during the study period of
CY2018-2022 will be reviewed, and the electronic medical record will be searched to determine the suspected
etiology/etiologies of RhD alloimmunization in each case.

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